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Mitochondrial complex I deficiency leads to increased production of superoxide radicals and induction of superoxide dismutase
However, recent clinical findings provided by Jain et al
(-)-Epigallocatechin-3-gallate protects against NO-induced ototoxicity through the regulation of caspase- 1, caspase-3, and NF-B activation
Patients with secondary carnitine deficiency accumulate organic acids which causes enhanced urinary excretion of carnitine in the form of acyl-carnitines [36, 37]
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