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it also suppresses the growth of platinum-resistant CRC and ovarian cancer cells, suggesting that combined treatments based on conventional drugs and glutamine-modulating compounds will yield clinically relevant results 43,44
The stability window interacts directly with the dosing schedule, and this is a practical planning point rather than a theoretical one: at 2.4 mg/week a 10 mg vial covers four weeks, which lands exactly at the outer edge of the in-use window
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