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The TRIUMPH-3 population had severe obesity and established cardiovascular disease, so that readout matters because it speaks to a higher-risk cardiometabolic cohort
In healthy people, this is manageable
But full correction of deficiency symptoms usually takes 4-8 weeks minimum
Semaglutide, marketed as Ozempic and Wegovy, effectively controls blood sugar and promotes weight loss but can cause fatigue through several mechanisms
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