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Glucagon-like peptide-1 (GLP-1) receptor agonists are a class of injectable medications used primarily for managing type 2 diabetes and, in some formulations, for weight management

Patients with pre-existing seizure disorders should inform their healthcare provider before starting weight loss injections, as metabolic changes could theoretically affect seizure threshold

Moreover, recent evidence indicates that mitochondrial complex I deficiency, linked to increased oxidative stress, promotes PD 279,280

In a study comparing the effects of GIPR and GLP-1R activation on -cell survival in response to streptozotocin challenge in mice, Maida et al