The most cited reasons for screening were persistently elevated liver enzymes, metabolic syndrome, obesity, and pre-diabetes/diabetes
Front Endocrinol (Lausanne) 12:645507
Mechanism [edit] Glutathione synthase catalyzes the chemical reaction ATP + gamma-L-glutamyl-L-cysteine + glycine ADP + phosphate + glutathione The 3 substrates of this enzyme are ATP, gamma-L-glutamyl-L-cysteine, and glycine, whereas its 3 products are ADP, phosphate, and glutathione
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