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[18] Many molecular events discussed alongside AOD9604such as cyclic AMP accumulation, protein kinase A activation, hormone-sensitive lipase phosphorylation, perilipin remodeling, and mitochondrial fatty-acid oxidationbelong to established adipocyte biology

Studies should identify the exact depot rather than referring generally to fat tissue. The currently cited evidence does not establish a universal conclusion that one specific visceral depot responds more strongly than all subcutaneous depots

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