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They work synergistically, addressing healing from multiple angles

Part IV: reactive oxygen species and oxidative damage in endometriosis Proximity of gametes and embryos to ROS from inflammatory response ROS are in female oviductal fluid and PF and function as normal signaling modulators of ovulation, embryo development and implantation (91, 92)

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However, the questioned toxicity of copper catalysts, even though well-established protocols of purifications (i.e., dialysis techniques) are available, has led to a strong demand of metal-free click reactions for biological applications