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An ideal experiment would likely be to start the mice in any one of the protection cells in the table on a high fat diet with no drug, then give them the protection drug midway through the trial while keeping them on a high fat diet, and see if they lose weight or maintain their obesity
For larger birds, 40C to 60C discharge rated packs are a safe bet (again for normal to sport)
They slow gastric emptying, prolong satiety, and may dampen neural reactivity to food cues that trigger binge episodes
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