GPxs, which participate in the processes of antioxidant protection and detoxification, are important enzymes that directly regulate ROS levels [28]
Kowdley 1 , Amarita Randhawa 2 , Jing Li 2 , Hiral Patel 2 , Christopher Gasink 2 , Sangeeta Sawhney 2 and Scott Isaacs 3 , (1)Liver Institute Northwest, (2)Intercept Pharmaceuticals, Inc., Morristown, NJ, (3)Emory University School of Medicine Background: Type 2 diabetes mellitus (T2D) is a common comorbidity associated with nonalcoholic steatohepatitis (NASH)
Whether cagrilintide or CagriSema preserves more lean mass than GLP-1 receptor agonists alone remains an open question that future studies need to address
It requires daily injections rather than weekly, which has reduced its use as semaglutide and tirzepatide have become available