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AhR activation promotes Treg cell generation by enhancing Lkb1-mediated fatty acid oxidation via the Skp2/K63-ubiquitination pathway
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Despite extensive preclinical support, clinical trials of these agents have yielded largely inconsistent and disappointing outcomes (summarized in Table 1), highlighting fundamental translational challenges
Ethical approval This study was approved by the Ethics Committee of the Plastic Surgery Hospital (Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China
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