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NADH consumption was detected at 340 nm, recorded in 1 min intervals over a period of 20 min
Functional analysis revealed that 41 genes formed five groups: (1) apoptosis-related genes, (2) oxidative stress- and ER stress-related genes, (3) cell proliferation- and EMT-related genes, (4) cytoskeleton-related genes, and (5) histone-related genes
Additionally, it was reported that trimetazidine (TMZ), a piperazine derivative, mediated activation of the GSH system and had antioxidant and cytoprotective effects in several myocardial injury models [210,211,212,213]
Extended-release formulations may reduce gastrointestinal intolerance
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