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220 An increase in mitochondrial mass and hyperpolarized mitochondria result in mtDNA damage, which affects T cell senescence

The muscles also prevent the pelvis from dropping when walking or running

If the molecular chaperone functions of HSP70 and HSP90 are impaired by genetic deletion, mutation, or pharmacological inhibition, cells may become less efficient at recognizing, refolding, or clearing misfolded proteins, thereby compromising proteostasis recovery (Rutledge et al., 2022

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