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For children and adolescents aged 2 to 18, providers assess BMI using a percentile scale based on gender and age, defining obesity as a BMI at or above the 95th percentile and overweight as falling between the 85th and 94th percentiles (3)

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these neoplasms are characterized by a high number of point mutations, mostly consisting in the so-called UV signature (cytosine to thymidine transitions at dipyrimidine sites)