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Semaglutide Timing and Meal Planning for Maximum Results Your injection day does not require fasting or special meal timing, but the days after injectionwhen semaglutide peaksare when appetite suppression is strongest

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Notably, tirzepatide (Zepbound) was not approved for weight management in patients with overweight or obesity until shortly before the patient-identification window closed, resulting in most patients in the tirzepatide cohort receiving Mounjaro, which was assumed to be used off-label for chronic weight management in the absence of T2DM