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The Best GLP-1 Supplements for Effective Weight Loss in 2025 Brittany Smith-Moretti Sep 10, 2025 12 min read GLP-1 , or glucagon-like peptide-1, is a hormone that your body naturally produces to regulate appetite and blood sugar levels
Conversely, the chronic exposure to the GLP-1RA Exendin-4 (Ex4) reduced the hypothalamic expression of the kisspetptin-1 (Kiss-1) receptors, with a marked reduction of the preovulatory LH peak and a delayed puberty onset [35]
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