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Inflammation research : official journal of the European Histamine Research Society

M1-like macrophages, characterized by elevated glycolysis, disrupted TCA cycle intermediates, enhanced ferritinophagy, and high ROS/NO production, naturally promote ferroptotic pressure

By protecting the mitochondria from exercise-induced oxidative damage and supporting faster clearance of metabolic waste, glutathione may help raise the threshold for exertion and reduce the severity and duration of systemic crashes