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The explanation for central body fat being more associated with NAFLD seems to lie in the fact that visceral adipocytes, which are more lipolytic than subcutaneous ones, store and mobilize triglycerides faster than those in other regions, increasing the supply of free fatty acids in the portal system, which stimulate gluconeogenesis and inhibit hepatic insulin clearance, contributing to elevated blood glucose and insulin levels and thus the development of insulin resistance (IR) ( 26 , 27 )
Magnetic Resonance in Medicine, 25(1), 94106
This is an additional tailwind for ESTA as their Mia platform is the highest cost option per patient, and has the potential to deeply penetrate the highest brackets of disposable income
AngII receptor type 2 (AT2) is generally considered to be an antagonist of the AT1 receptor, regulating the relaxation of the smooth muscle (92)
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