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Systemic Side Effects: Sermorelin is generally well tolerated, and because it triggers endogenous hormone release, systemic side effects tend to be mild for most patients
BMC Cardiovasc
Results of a phase IIa trial published in 2024 demonstrated that a once-daily 10mg, 20mg and 50mg dose of monlunabant all led to statistically significant weight loss compared with placebo after 16 weeks
However, development for this purpose was stopped due to side effects, such as severe nausea and increased blood pressure, which limited its clinical usefulness
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