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These medications often produce more immediate, powerful sedation but can disrupt normal sleep architecture, reduce deep sleep, and cause dependency with regular use
g Given
The human pharmacokinetics come from a combination trial
The most commonly reported side effects in clinical trials include: Nausea Vomiting Diarrhea Constipation Most of these symptoms were mild to moderate and tended to improve over time as the body adjusted to the medication, especially when doses were increased gradually
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