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The weekly two days off and the four week break between courses are both aimed at the same thing, which is preserving receptor sensitivity and letting your own pulsatile growth hormone release resume
Clinicians should evaluate for contraindications specific to GLP-1 receptor agonists, including: Personal or family history of medullary thyroid carcinoma Multiple Endocrine Neoplasia syndrome type 2 History of pancreatitis or gallbladder disease Severe gastroparesis or gastrointestinal disease History of suicidal ideation or behavior Pregnancy or planned pregnancy (pregnancy testing when appropriate) Diabetic retinopathy (requires monitoring in patients with diabetes) Baseline investigations should include TSH, free T4, complete metabolic panel, lipid profile, and hemoglobin A1c (if diabetic or prediabetic)
Seek urgent help if you develop: Severe, persistent abdominal pain may be a sign of pancreatitis
G (00:39:13):Prevent it or delay the progression of the disease
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