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The one constant is consistency of timing and route for a mechanism that works by gradually shifting cellular metabolism, day-to-day steadiness matters more than any single dose
Each delivery route has practical differences beyond clinical efficacy that may influence which option is best for a given patient
If a scheduled amount is missed, there is no approved guidance and doubling is not supported by evidence
Vegans and "patients with diseases like Crohn's and colitis as well as people with pernicious anemia are also particularly vulnerable to deficiency," added Silverstein
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