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Intravenous (IV) Glutathione IV glutathione is the fastest-acting form, delivering the antioxidant directly into the bloodstream

However, it is important to note that most of the current evidence is based on animal models, and there is limited high-quality human clinical data

The presence of oxidative stress markers like lipid peroxidation, neutrophil reverse trans-endothelial migration (rTEM) and high neutrophil to lymphocyte ratio in patients with COVID-19, facilitates identification of high-risk individuals early in the course of the disease preventing their sudden deterioration (Laforge et al., 2020)

This approach provides both the systemic gene expression modulation from injections and concentrated local delivery from topical application