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Ingold, I., Berndt, C., Schmitt, S., Doll, S., Poschmann, G., Buday, K
2024;25(4): bbae350
Chondrocyte dedifferentiation was majorly characterized as the reduced expression of COL2 and ACAN and enhanced expression of type I collagen and versican ( COL2 expression, but not ACAN ( In addition to dedifferentiation, another consequence of in vitro expansion is replicative senescence, which also significantly influences chondrocyte function
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