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Moreover a recent systematic review and meta-analysis assessed the impact of different drugs for the treatment of diabetes on the risk of developing dementia, mild cognitive impairment, or cognitive decline highlighting that incretin-based therapies, particularly GLP-1 receptor agonists, were associated with a significant reduction in the risk of cognitive impairment compared to other antidiabetic treatments

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Reports of isotope studies, including the use of the stable isotope 13 Clabeled B12 (Devi et al., 2020), indicate that 50% of an oral dose of 1g is absorbed, 20% of a 5g dose, and 5% of a 25g dose, as shown in Figure 22b.3