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3.1 T1D-associated genes: impact on immune function Approximately 40-50% of the genetic risk of developing T1D is attributed to the class I and II MHC/HLA region, with class II being the most significant, as it is essential to the adaptive immune system ( Figure 1 ) (7, 13, 50)
Constipation (8%), nausea (7%), and stomach pain (7%), among individuals receiving eluxadoline, were the most frequent side effects (61)
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