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Retatrutide is an investigational triple agonist that simultaneously activates three hormone receptors: glucagon-like peptide-1 (GLP-1), glucose-dependent insulinotropic polypeptide (GIP), and glucagon receptors
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The existing evidence, while promising, does not establish efficacy, optimal dosing, treatment duration, or long-term outcomes for this indication
2004;286:R14350
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