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For patients taking warfarin, which requires careful monitoring through international normalized ratio (INR) testing, the initiation of semaglutide warrants consideration of more frequent INR monitoring during the titration phase

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On the other hand, metformin-treated mice displayed a slight decrease in body weight, fat mass, and circulating glucose, insulin, and leptin levels, which was associated with a modest reduction of HOMA-IR index and a drop in daily food intake (Fig