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[1] [7] Additionally, because glucagon promotes glycogenolysis and gluconeogenesis, there is a theoretical concern regarding glucose management in people with type 2 diabetes, although the GLP-1 and GIP components appear to counterbalance this effect in practice
both treatments can support meaningful, sustainable weight loss , but they differ in how they act, likely outcomes, and practical considerations like cost and coverage
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Topol has been a loud voice of caution against the untested drugs
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