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Another issue with clinical translation is patient genetic variation in the expression of NAD + synthesis genes, or lifestyle conditions changes, including exercise regimens, that would influence the effectiveness of interventions

Methods: We systematically searched PubMed, clinicaltrials.gov, FDA and EMA product information on GLP-1 agonists and SGLT2 inhibitors in pregnancy and lactation from inception up to 19 April 2022 without language restrictions

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