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designed PLA-based NPs loaded with microRNAs (miR-21) that induce cell apoptosis and prevent tumor development [247]
Higher concentration: mixing to 5 mg/mL keeps injection volumes small even at the top of the range useful when titrating toward 4.5 mg, the dose linked with the largest weight reductions in early trials [4]
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In agreement with prior literature [35], this result suggests that GSH is not stable in plasma at 4 o C, and thus samples should not be stored at this temperature
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