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Making the Most of Your Glutathione To optimize your existing GSH levels: Avoid overexposure to oxidative stressors like UV rays and environmental pollutants
Results GSH depletion induces cell death in RPE cells To evaluate the effect of GSH depletion on the RPE cells, we used three different approaches: depletion of Cys 2 from cell culture media, treatment with buthionine sulphoximine (BSO, 1000 M) to block de novo synthesis of GSH, or treatment with erastin (10 M), an inhibitor of system x c 1
Kisspeptin is the notable exception, dosed at 1 to 10 mcg/kg in clinical research
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