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Description

In a mouse model of shoulder arthrofibrosis, multiple intraarticular injections of human relaxin-2 restored range of motion and eliminated capsular fibrosis

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Permeation across this protective barrier is actively mediated by the organic cation/carnitine transporter known as OCTN2 (SLC22A5)

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It takes place primarily in liver cells, the liver being the bodys principal site of glutathione production and export

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