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This value is adequately adjusted with the CRP reductions associated with the use of semaglutide observed in some of the studies included in this review (range between 39.1% and 59.6%) ( Evidence from epidemiological studies has shown that elevated CRP levels, a surrogate for systemic inflammation, are associated with increased cardiovascular risk ( In clinical practice, CRP values exceeding 3 mg/L are considered as a marker of cardiovascular risk ( Several drugs evaluated in the field of cardiovascular prevention have shown to simultaneously have an anti-inflammatory (CRP lowering) and cardioprotective effect (decrease in cardiovascular atherosclerotic events)

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