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If an oligourea portion placed in the middle of the peptide induced a torsion or an elongation that is not exactly the same as the polypeptide it replaces, a drastic negative impact on the affinity would be expected
Hydroxocobalamin has a longer retention and is used for specific patient needs
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Delfanti G, Cortesi F, Perini A, Antonini G, Azzimonti L, de Lalla C, et al
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