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Subtle improvements in skin brightness may appear around 3 to 4 weeks
References state that the dysbiosis is likely to be responsible for early stage PD GI-related problems, including constipation, with a notable increase in bacterial families that include Lactobacillaceae, Verrucomicrobiaceae, Bradyrhizobiaceae, Bifidobacterium , and Akkermansia (Baldini et al., 2020
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Rotating between regions, for example abdomen one week and thigh the next, is preferable for long-term use
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