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Phase 2 trial in type 2 diabetes (Lancet 2023) showed similar additive benefit for the combination
Early data shows promising weight loss and particularly strong effects on liver fat reduction, making it potentially valuable for patients with non-alcoholic fatty liver disease
Haematological disorders require specialist haematology input, with treatment tailored to the specific diagnosisranging from observation to chemotherapy for malignant conditions
Mechanism of action Disrupts FOXO4p53 interaction in senescent cells
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