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In recent years, clinical practice has developed many simple, cheap, and effective alternative quantitative indicators, such as BMI, waist circumference, waist-to-hip ratio, wrist circumference [130]and other anthropometric markers

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Safety, Tolerability, and When to Pause or Reduce Dosing Gastrointestinal side effectsnausea, vomiting, constipation, and diarrheaare dose-related and most common during escalation phases