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Conditions like pernicious anaemia (an autoimmune disorder where your body cant absorb B12 from food), certain stomach conditions, medications that reduce stomach acid, or even gastrointestinal surgeries (like weight loss surgery) can prevent your body from properly taking in B12, even if youre getting enough in your diet
Similar to the gut barrier, the brain has its own protective barrier that allows necessary substances to enter and exit while shielding the brain from harmful pathogens
PMID 15126349
Presented for research literature review only Soszyski M et al
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