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In some individuals, particularly early in treatment, these physiological effects may be accompanied by gastrointestinal symptoms such as nausea or early fullness
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Necroptosis is characterized by the excessive accumulation of the products of oxidative stress, such as lipid hydroperoxides [218], end products of glycation [219], and increased activity of bioenergetic pathways, including glutaminolysis [220, 221]
PMID: 28469522
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