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Identification of the metabolic differences between microbial pathogens and their hosts, as well as the design of species-specific antimicrobial agents targeting the differential metabolic pathways, therefore represent the most promising fields of research and are strongly supported by recent developments in biological methodology and system biology that allow a better understanding of pathogenic mechanisms at various levels [8, 22, 59]
The specific NOS isoform or pathway component involved may differ between experimental systems and tissue contexts
Studies show Epithalon reduces formation of chromosomal aberrations caused by oxidative stress in bone marrow cells, suggesting DNA-protective antioxidant effects
