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Recently, the pharmacotherapy of MASLD mainly focuses on three parts of mechanisms: anti-inflammatory (ASK1 inhibitors), anti-diabetic (GCGR agonists, PPAR agonists), and prevention of lipotoxicity (FXR agonists, FGF21 analogues) (Wei et al., 2024)
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One important factor influencing the efficacy of intra-articular drugs is their residence time within the joint
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