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Not only that, a graphite nanocapsule formed by nitrogen-doped carbon nanotube cups (NCNC)effectively plugged by chloroauric acid to reduce sodium citrate by gold nanoparticles can effectively deliver paclitaxel to tumor-associated MDSCs and significantly downregulate the expression of TGF- in MDSCs, which not only inhibited the immunosuppressive phenotype of MDSCs but also differentiated them into DCs thereby reversing their immunosuppressive activity (121)
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