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New formulations, such as oral drugs that are easier to take than injections or longer-lasting drugs that need to be taken less frequently, could increase uptake and adherence
Allergic reactions (rash, itching) in susceptible individuals
Substantial weight loss may reduce knee loading and improve symptoms, but clinically relevant loss of lean mass may worsen sarcopenia, quadriceps weakness, balance, walking capacity, and postoperative recovery
To allow rapid and specific equilibration with the glutathione pool, fusion constructs with human glutaredoxin 1 (GRX1) were generated and characterized in vitro
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