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Once weekly injections at 0.25 to 2.4 mg: Semaglutide (Ozempic or Wegovy) or compounded semaglutide Once weekly injections at 2.5 to 15 mg: Tirzepatide (Mounjaro or Zepbound) or compounded tirzepatide Once daily injections at 0.6 to 3 mg: Liraglutide (Victoza or Saxenda) Once weekly injections at 0.75 to 4.5 mg: Dulaglutide (Trulicity) Oral tablet taken daily: Semaglutide (Rybelsus) or orforglipron (Orfoglip) Step 3: Check the pen or vial appearance
In the brain, GLP-1 receptors act like a stop light and tell certain areas of the brain to stop releasing dopamine, the feel-good chemical that reinforces compulsive or addictive behavior, like alcohol consumption or over-eating, Varisco says
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Tirzepatide activates both GLP-1 and GIP pathways, while semaglutide primarily activates the GLP-1 pathway
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