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Recent research has primarily focused on -6 PUFAs (e.g., linoleic acid, gamma-linolenic acid, dihomo-gamma-linolenic acid, arachidonic acid, and adrenic acid) and -3 PUFAs (e.g., alpha-linolenic acid, eicosapentaenoic acid, and docosahexaenoic acid) in the context of ferroptosis

Numerous iron genes have been identified in hereditary iron overload syndromes, with hemochromatosis (deregulation of intestinal iron absorption) being the most common

GSH deficiency is associated with a number of central nervous system diseases such as Multiple Sclerosis, Autism, Bipolar disease, Alzheimers, and Parkinsons disease