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Pentameric nCRP and CRP peptides 7782, 174185, and 201206 can control the inflammatory response resolving inflammation by reducing inflammatory cell endothelial adhesion and tissue migration, and the described CRP-mediated enhanced monocyte chemotaxis could be explained by local generation of mCRP (190, 191)

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Patients with pre-existing osteoporosis, osteopenia, or elevated fracture risk may warrant baseline dual-energy X-ray absorptiometry (DXA) scanning to establish a reference point for future comparison