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Thymosin 4 is a 43-amino-acid, roughly 5 kDa polypeptide. TB-500, as supplied by most research vendors, is a short synthetic fragment corresponding to the actin-binding motif within that larger sequence the region shown to carry much of the peptide's angiogenic activity in endothelial migration assays. The distinction matters when you calculate on a molar rather than a mass basis

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