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Phase 2 study of AKB-6548, a novel hypoxia-inducible factor prolyl-hydroxylase inhibitor (HIF-PHI) in patients with end stage renal disease (ESRD) undergoing hemodialysis (HD)
This result suggested they might be recognizing nontarget features, such as the GGS linker between lysozyme and RNAP, rather than authentic substrate residues
The mechanisms involved in acute enhancement of power output and reduced lactate accumulation are possibly (in higher intake levels) also responsible for the reduced mean values of power seen with long-term intake
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