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Pharmacotherapy options, such as orlistat, phentermine-topiramate, and naltrexone-bupropion, can support weight loss, though they may cause adverse effects and do not work effectively for all patients
Mol Endocrinol 25: 2134-2143, 2011
Who should not use Wegovy
Recombinant lines expressing a single melanocortin receptor subtype are the cleanest system available, and for a non-selective agonist they are close to essential, because they are the only way to attribute a response to one receptor without pharmacological subtraction
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