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Amylin also influences bone metabolism through interactions with calcitonin and CGRP pathways, potentially offering protective effects against bone degradation

Using the International Diabetes Federation definition of metabolic syndrome (central obesity plus any two of the following: raised triglycerides, reduced high-density lipoprotein cholesterol, raised blood pressure, and raised fasting glucose), the researchers found that 9% randomized to TAF/FTC+DTG, 5% randomized to TDF/FTC+DTG, and 3% randomized to TDF/FTC+EFV had metabolic syndrome at week 96

10.1146/ANNUREV.GE.22.120188.003215 105 LiuS.LiJ.TaoY.XiaoX